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But again, larger, long-term studies are needed to fully establish these benefits. Short-term studies suggest L-theanine is relatively well tolerated in many adults, but long-term safety data are limited

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Toxicol Appl Pharmacol 268:7989 Yang X, Greenhaw J, Shi Q, Su Z, Qian F, Davis K, Mendrick DL, Salminen WF (2012a) Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity

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