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bypassed: Secretagogues maintain the hypothalamic-pituitary feedback loop

The most common side effects of GLP-1 RAs include: Nausea and vomiting Abdominal pain and bloating Indigestion or acid reflux (heartburn) Constipation or diarrhea Weakness during exercise Headache These side effects may be bothersome, but are not dangerous

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The decline in cerebral glucose metabolism has been consistently associated with the pathological progression of AD and subsequent cognitive impairment

Thus, inviting companies to monitor the safety of their own products provides them with the strongest possible incentive for failing to do soan instance of the law of unintended consequences