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doi: 10.3389/fendo.2023.1133000 Received 28 December 2022 Accepted 13 March 2023 Published 24 March 2023 Volume 14 - 2023 Edited by Silvia Martina Ferrari, University of Pisa, Italy Reviewed by Sabrina Rosaria Paparo, University of Pisa, Italy

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The expression of NF-KB in BAL fluids is much lower in asthma patients than in healthy subjects due to greater bioavailability of NO in the respiratory tract (99)

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The observed increase in apoptosis following bromadiolone exposure may therefore result from APC inhibition, which disrupts these cytoprotective pathways and promotes caspase-mediated cell death

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