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Comparative evidence from other weight loss methods shows that cold intolerance is commonly reported following bariatric surgery and with very low-calorie diets, supporting the hypothesis that the sensation relates primarily to the weight loss itself rather than the specific mechanism

S., Mani, H., Banaudha, K., Maheshwari, R

That pooled fluid can feel like a small bubble

Zhao X, Huang K, Zheng M, Duan J

Electrolyte imbalance may also cause fatigue and muscle cramps

Grace Hamilton, a study participant who has been on GLP-1s since her early 20s, said she has noticed several impactful changes to her brain since being on the medication