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long-term use may cause gallbladder issues ([web:0])

Background: Incretins were discovered after it was observed that administration of an oral glucose load leads to a much greater stimulation of insulin release than a comparable glucose load given intravenously (Hansotia & Drucker, 2005)

The decision of which medication to prescribe, if any, is based on your providers determination as to which medication is considered the most effective and safe for you