It is also authorised for use in weight loss and weight management in adults aged 18 and over, alongside a reduced-calorie diet and increased physical activity
Additionally, they improve circulation and mobility, and even promote skin whitening
Over time, if ePA contributes even a small percentage improvement in medication adherence or disease outcomes, the ROI is substantial
they are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or MEN 2
If an oral formulation achieves only 1% bioavailability (matching oral semaglutide), you would need roughly 80 times the injectable dose to achieve equivalent blood levels
Some practitioners actively recommend combining them, with the probiotic supporting gut health while the medication provides direct GLP-1 receptor activation