For the electron coupling assays, respiratory substrates (10 mM pyruvate + 2 mM malate, 10 mM succinate + 2 M rotenone, 80 M palmitoyl-carnitine or octanoyl-carnitine + 0.5 mM malate or 10 mM glutamate + 10 mM malate) were diluted in MAS buffer with BSA (70 mM sucrose, 220 mM mannitol, 10 mM KH 2 PO 4 , 5 mM MgCl 2 , 2 mM HEPES and 1 mM EGTA, pH 7.2, in 0.2% FA-free BSA) and added to mitochondria
L-carnitine is a naturally occurring compound that plays a key role in transporting fatty acids into the mitochondria for energy production
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Dans cette conformation, la face hydrophobe de cette hlice amphiphile est en interaction avec des rsidus hydrophobes entourant le site actif tandis que sa face hydrophile interagit avec des molcules d'eau
The burden of hypercholesterolemia and ischemic heart disease in an ageing world
But these could be related to diabetes and not Trulicity