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Most incretin weight-loss therapies are injected subcutaneously, but oral semaglutide is already licensed in the UK for T2DM as Rybelsus, while its manufacturer Novo Nordisk has published positive phase III results (OASIS-4, NCT05564117) for its 25mg semaglutide pill for weight loss 6
Nachnani JS, Bulchandani DG, Nookala A, Herndon B, Molteni A, Pandya P, Taylor R, Quinn T, Weide L, Alba LM
Participants received either tirzepatide at 5 mg, 10 mg, or 15 mg, or placebo, injected once weekly for 72 weeks
The difference between average results and exceptional results often comes down to what you do alongside the medication
For eligible patients, semaglutide can be an effective adjunct to a healthy lifestyle, supporting both metabolic health and weight reduction when combined with diet and exercise
It is characterized by an accumulation of subcutaneous fat, most commonly in the legs and occasionally arms
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