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Mol Cell Endocrinol 422:1830 Gengler S, Mcclean PL, Mccurtin R, Gault VA, Hlscher C (2012) Val (8) GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice
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Reactions that worsen with dose escalation Tirzepatide treatment typically involves gradual dose increases
AI is similar to the RDA, which is a daily intake level thought to meet the requirements of 97.5% of people, but AI is based on weaker evidence than RDA
See Table 1 for which patient groups should not receive GLP-1 therapy[511,18] Cautions for GLP-1 and GIP therapy use GLP-1 and GIP therapy should be used with caution in certain patient groups
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