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The mechanistic comparison is particularly interesting: CagriSema adds amylin signaling to GLP-1, while retatrutide adds glucagon and GIP signaling
Other drug interactions may occur with selective serotonin reuptake inhibitors (SSRI) antidepressants, antihypertensives, and antipsychotics
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Conclusions Energy and cardiovascular regulation represent the two crucial functions of the autonomic nervous system, while GLP-1RAs and SGLT-2is signaling may generate different effects on the central nervous system
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