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Mixed meal tolerance tests (MMTT) results were compiled to assess metabolic responses

Both the GIPR and GLP1R are expressed in the central nervous system, wherein receptor activation produces anorectic effects enabling weight loss

GLP-1 and the NVU GLP-1 receptors are expressed on various cell types within the NVU, including neurons, astrocytes, microglia, and endothelial cells

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Researchers may use it to explore pathway mapping, molecular mechanism readouts, and proteinprotein interaction dynamics in non-clinical laboratory models