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7 Why Even Small Weight Loss Matters People who are overweight (BMI in the 25 to 30 range) drop less weight on GLP-1s than those with clinical obesity, losing just 5 to 10 percent of their body weight on average versus 15 to 20 percent for the obese cohort

The medication maintained therapeutic activity across the full seven-day period, preventing the appetite rebound that shorter-acting compounds may produce

For educational context, start with the MelanotanII hub, then the deep dives for mechanism, evidence, safety and status, and quality and COA

[PMID: 38236015] PubMed record related to this compound for laboratory literature review

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