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We further systematically evaluate the therapeutic potential of ferroptosis-targeting agents in promoting diabetic wound healing, thereby providing a theoretical framework for developing precision interventions against ferroptosis
J Biol Chem 277:2694426949 Couturier J, Przybyla-Toscano J, Roret T, Didierjean C, Rouhier N (2015) The roles of glutaredoxins ligating Fe-S clusters: sensing, transfer or repair functions
Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a key transcription factor upregulating the antioxidant response element (ARE)-mediated expression of antioxidant and detoxifying enzymes, and the Nrf2-antioxidant pathway is critical in host defense against acute lung injury (ALI) 24
In contrast to GST , the expression of two host genes encoding an enolase and a cinnamyl alcohol dehydrogenase did not change significantly during this tripartite interaction (Daval et al., Beneficial, symbiotic fungi can not only promote plant growth and nutrient uptake but they are also able to induce key defense reactions in plants including the activation of GSTs
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For the liraglutide group participants were started on: 2 metformin, 2 empagliflozin, 1 canagliflozin, 1 semaglutide
