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Miras says that many people who regain weight after medication or dieting experience a change in their body composition which could potentially be even worse for their long-term health than if they had simply maintained their existing weight

Clinical Evidence and UK Guidance on Ozempic Use The evidence base for semaglutide's efficacy and safety profile derives primarily from the SUSTAIN clinical trial programme, which enrolled over 8,000 participants across multiple international studies

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It has required a structural adaptation of workflows, verification processes, and patient communication strategies

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