Not just weight reduction, but reductions in heart attack, stroke and cardiovascular death. Those findings helped reposition GLP-1s as long-term metabolic therapies rather than short-term fixes
Metformin: update on mechanisms of action and repurposing potential
Key takeaways: Hashimotos and hypothyroidism do not automatically disqualify you Only medullary thyroid cancer and MEN-2 are true contraindications Weight loss may require thyroid medication adjustment Personalized endocrine care makes all the difference Whether youre located in Lafayette, San Francisco, the Bay Area, or anywhere in California via telemedicine , these decisions for my patients are always made through thoughtful, one-on-one discussions
In an insulin-resistant milieu, insulin may competitively inhibit IDE, which impedes the degradation of A proteins, increases their neurotoxicity, and contributes to the onset of AD (Scherer et al., 2021
They need to be repeatable
10.1126/scisignal.2002329 51 KuhnM.VON MeringC.CampillosM.JensenL
