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The Endocrine Society research showed that men who lost 10% of body weight with GLP-1 medications saw their normal testosterone proportion rise from 53% to 77%, without any testosterone supplementation
GHS requires endogenous hypothalamic GHRH for maximal GH stimulation
On average, patients lose about 20 to 25% of their body weight with surgery
Abbas Key Points One shouldnt consider GLP-1s to be a lifelong therapy GLP-1s can be useful in training for lifestyle change GLP-1s have an upper limit of effectiveness that may not work for 40+ BMI patients Medication and surgery can work symbiotically With the advent of weight loss-approved GLP-1 drugs like Wegovy and Zepbound, there is renewed hope in the fight against excess weight and obesity
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In the pivotal BaxHTN trial, the 2 mg dose lowered systolic blood pressure by approximately 15.7 mmHg from baseline, with a placebo-adjusted reduction of about 9.8 mmHg
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