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When shigatoxin was injected into transgenic mice bearing a chloramphenicol acetyltransferase (CAT) reporter gene that indicates TNF synthesis, CAT activity was induced within the kidney, but not in other tissues

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GLP-1 therapy should not replace established antihypertensive medications and must be prescribed according to NICE guidance for licensed indications

Sun J-M, Shen L, Shah MA, Enzinger P, Adenis A, Doi T, et al

Ghallab A, Myllys M, Holland CH et al (2019) Influence of liver fibrosis on lobular zonation

This landmark study randomized 17,604 adults with overweight or obesity (BMI 27 kg/m) and established cardiovascular disease to once-weekly subcutaneous semaglutide 2.4 mg versus placebo [1]