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The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)
It showed 41.7 mm WOMAC pain reduction versus 27.5 mm on placebo over 68 weeks
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Providers often request baseline blood work and repeat tests every 8 to 12 weeks in addition to monitoring changes in pain levels, mobility, and day-to-day function
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These include TNF-alpha, IL-1 beta, and IL-6, all of which drive joint destruction in inflammatory arthritis
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