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Considering the many limitations of intravenous glutathione, it is prudent that dermatologists refrain from administering such injections for skin lightening until further trials and high quality studies establish a favourable benefit versus risk ratio that justify its use [Box 7]

These trials revealed the modulation of leukemic gene expression and disease stabilization in some patients, 429,430,431,432 although neurotoxicity and limited monotherapy efficacy emphasized the need for rational combination therapy and stratification

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(PubMed) Kim HJ, Chang WK, Kim MK, Lee SS, Choi BY

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