Surgeons should consider how the timing of elective procedures might shift if GLP-1 therapy is inducing substantial weight loss or anatomical change, which is relevant for bariatric, abdominal or head and neck surgeries
The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway
D'Agostino A, Ferrara P, Terzoni S, et al
The SURMOUNT-1 trial showed average weight loss of up to 22.5% of body weight at the highest dose
However, it is essential to approach the use of GLP-1 agonists with caution, particularly when considering their compatibility with osteoporosis treatments
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