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Long-term watch items beyond the common GI events that fade within weeks include gallbladder disease (cholelithiasis 1.1% in trials), acute kidney injury (0.5%), and rare cases of pancreatitis (under 1%)
Phillips KA, Epstein DH, Preston KL (2014) Psychostimulant addiction treatment
A total of 26 male SD rats underwent the MCAO procedure to induce focal stroke
Glutathione is also considered safe, though oral absorption can be limited unless using liposomal or sublingual forms
The treatment works by affecting melanin production so sun damage can ruin the desired results
So the fair summary for BPC-157 within KLOW is: strong and interesting preclinical data, a real mechanistic rationale, and a near-total absence of the human efficacy and safety evidence that would justify confidence in the systemic claims made for it
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