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Ingredients: B12 Methylcobalamin 2000mcg (2mg) Benzyl Alcohol 15% Sodium Chloride 0.9% Water for injection, ph (range 4.5-7.0), adjusted with Sodium Hydroxide

The single compound addresses multiple aging concerns simultaneously

Retatrutide a triple agonist of GLP-1, GIP, and glucagon receptors (half-life ~6 days), promoting insulin secretion, hepatic fat oxidation, appetite suppression, and energy expenditure

Improved Sleep Quality: B12 is involved in producing melatonin

That is a large part of why B12 has such a favorable safety record

REDEFINE 1 ClinicalTrials.gov number, NCT05567796.) Are you a member of an institution such as a university or hospital?Learn more about Institutional Access Notes This article was published on June 22, 2025, and updated on July 28, 2025, at NEJM.org