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Clinicians should also assess whether patient expectations are realistic

Dose step-up Starting on a lower dose and raising it gradually - common in these trials

tBHP, tertbutyl hydroperoxide

However, the lack of significant results favoring a neuroprotective effect of GLP-1R agonists may be due to early business-related withdrawal of sponsor support (Mullins et al., 2019)

Dietary cobalamin deficiency