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Am Fam Physician 76:3916 Wu Y, Zhang X, Bardag-Gorce F, Robel RC, Aguilo J, Chen L, Zeng Y, Hwang K, French SW, Lu SC, Wan YJ (2004) Retinoid X receptor alpha regulates glutathione homeostasis and xenobiotic detoxification processes in mouse liver
Even foods that are high in natural sugars, such as dried fruits, may contribute to side effects if eaten in large amounts
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Conclusions The present review provides a systematic up-to-date summary of progress in development of transporter-utilizing (pro)drugs and nanocarriers for brain delivery of drugs
Additionally, individual patient factorsincluding baseline gastric emptying rate, previous gastrointestinal conditions, concomitant medications, and genetic variations in drug metabolismcontribute to the considerable inter-patient variability observed in clinical practice
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