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Isaacson, M.D., and Jonathan Isaacson, M.D
As discussed earlier, Koeth et al.'s study on gut microbiota-induced TMAO in stable patients undergoing cardiac evaluation showed significant dose-dependent associations between plasma L-carnitine levels and risks of coronary artery disease, peripheral artery disease, and overall CVD after correction for common CVD risk factors [18]
This helps explain why many people taking GLP-1 medications report significant reductions in their desire to eat, especially high-calorie or sweet foods
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as a rule, the higher the degree of CSD the higher the tumor mutation burden (TMB) (on average: 30 mutations/megabase in high-CSD melanoma
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