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In addition, the treated groups revealed significant upregulation of 7nAChRs at both gene and protein levels, resulting in improved brain damage [36]

Two MTHFR genes commonly studied are C677T and A1298C (these labels indicate the mutations appearance and location on the gene)

It is a measurable shift that correlates with perimenopause onset, not with menopause itself

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Clinical evidence reveals a pro-inflammatory polarization state in the COPD lung: Th17 cells and downstream factors including IL-17A and IL-23 are elevated, while Treg cells are reduced in number and secrete less IL-10 and TGF- (51, 75)

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