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Furthermore, compared with patients who received radiotherapy alone, breast cancer patients who underwent CR concurrently with radiotherapy exhibited a significant reduction in the serum levels of immunosuppressive cytokines, suggesting potential benefits of CR in mitigating radiation-induced immunosuppression

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Butyrate activated the hormone signaling such as protein kinase B (PKB/Akt), and increase the expression of glucose transporter (Glut4) (116, 123, 124, 130)