For Hereditary B12 Malabsorption If you suffer from Imerslund-Grasbeck disease, your vitamin B12 malabsorption will be treated with hydroxocobalamin injected into the muscle at a dose of 10 mg per day for 10 days followed by monthly injections for life
If a patient is severely deficient, a physician might recommend an injection every other day or daily for the first week to rapidly saturate the bodys tissues
But no matter how much water you choose to use, you would get ten 0.5mg shots out of your 5 mg vial
If you think you might have a vitamin B deficiency, your doctor can test your blood levels and discuss whether shots might be beneficial.
However, a very small percentage of B12 from a supplemental dose is absorbed by passive diffusion, rather than by intrinsic factor, such that vegans can make up for taking B12 only once per day, or even only once per week, by taking larger doses than normally provided by food
doi:10.1136/bmjopen-2014-006964