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The decrease in LV mass and pericardiac adipose tissue might be closely associated with the reduction in HF events that were observed in the main SUMMIT trial [70]
Patients appreciate avoiding long wait times and in-person clinic visits, receiving medications shipped directly to their door, and having telehealth appointments that fit into their busy schedules
This was a big study
They concluded that silymarin is safe and effective as an herbal galactagogue, capable of boosting lactation without affecting breast milk quality.20 We should mention that some sources say to avoid using milk thistle while breastfeeding, as one can't conclusively attest to its safety for either the mother or the infant based on the current research
For a small-molecule drug, the FDA ANDA pathway requires bioequivalence demonstration a pharmacokinetic equivalence study showing that the generic delivers the same active ingredient exposure as the reference listed drug
