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10.1371/journal.pone.0122371 162 YuJ.YuanQ.SunY

doi: 10.3390/JCM13164674 38 DoranACMellerNMcNamaraCA

Future prospective studies should use more extensive fatigue questionnaires, such as the Fatigue Assessment Scale (FAS) (64) or the 11-point fatigue numeric rating scale (NRS) (65, 66)

However, MRP1 is unlikely to adopt the ATP-dependent transition from inward to outward conformation to transport a single molecule of GSH, because if such was the case, a strong stimulated GSH efflux would require the hydrolyzation of a large number of ATP, and this would not comply with the very low ATPase activity of MRP1 57

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