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SCENIC regulon activity, scDRS-derived AD enrichment scores and Class C AD module scores were modeled with linear mixed-effects models including mouse identity and sequencing pool as random effects, followed by two-sided lsmeans t -tests with BH correction

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Outro aspecto que despertou interesse dos pesquisadores foi a capacidade da molcula de influenciar a atividade de milhares de genes humanos relacionados ao crescimento nervoso, resposta antioxidante, ao reparo celular e inflamao