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Israel Chaikoff, an observation now known as the Wolff-Chaikoff effect (25, 26)

Possible Side Effects Potential side effects may include: Mild headache Nausea Stomach discomfort Allergic reactions (rare) Patients should discuss medical history and medications with their doctor before treatment

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Donor compartments received 3-PLG-dopa or 3-PLG-dopa-A-GSH (100 g/ml) diluted in phenol red-free DMEM/HAMs F-12 medium supplemented with 5% FBS and the model was incubated for 24 h

The most common adverse reactions reported in clinical trials were injection site reactions (erythema, pruritus, pain) occurring in approximately 8-13% of patients

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