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Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, et al

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Historical Background In the 1960s, it was shown that orally administered glucose induces a much stronger insulin response than that induced by intravenously administered glucose, despite the similar resulting plasma glucose levels

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Extracted from the duodenal mucosa of hogs, this proved to be a potent inhibitor of gastric secretion and stomach movements