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Still, traditional protocols require a six-month behavioral therapy trial before medication considerationa practice increasingly questioned as data on early non-responders emerges

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Chemical Stability Acetyl-L-carnitine is stable in neutral to acidic aqueous solutions (pH below 9) but degrades rapidly at alkaline pH values greater than 9, with significant loss of integrity observed after short exposure times at room temperature [5]

The longest splicing variant of the SLC22A5 gene codes for an OCTN2 variant called OCTN2VT containing an insertion of 24 amino acids in the first extracellular loop, that seems to be localized in the ER (Figure 2