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On the NHS, liraglutide is still listed for specialist Tier 3 weight management services under NICE guidance (TA664), but its now rarely the first choice, having been largely replaced by Wegovy and Mounjaro
Both medications contain the same active ingredient: semaglutide
Evidence Quality Gap The most important dimension of this comparison is the quality and scale of the clinical evidence
Tirzepatide (Mounjaro) Based on results from a 72-week trial, estimated weight loss at 68 weeks is approximately 22% for the highest dose (15 mg)
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