The 2006 human study that Protandim quoted above is only a half-truth: yes, there was a 40% decrease in oxidative stress in study subjects using the TBARS test (which is not considered to be a reliable marker.) The methodology was also a mess
BPC-157 administration attenuated gastric lesions, reduced esophagitis severity, strengthened anastomotic integrity, and markedly increased pressure at both the anastomotic site and pyloric sphincter
In one study, lactic acid bacteria with high ACEI activity, Lactiplantibacillus plantarum B (formerly known as Lactobacillus plantarum ), Lactobacillus gasseri A , Lactiplantibacillus plantarum R5 (LPR5), and Lactiplantibacillus plantarum R7 (LPR7), showed antihypertensive effect in rat models with pregnancy-induced hypertension (49)
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A common approach is 8-12 weeks active, 8 weeks off, then reassess whether another cycle is needed