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For the behavioral experiment of SPF mice injected Ex-4 and ABX mice injected Ex(9- 39), mice were tested for OFT at 10 weeks of age, EPM at 11 weeks of age, and novel object recognition test at 12 weeks of age
Dose Range: 1.02.0 mg per injection
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Observations from PIONEER REAL Netherlands add to those previously reported in the SURE Netherlands study and highlight that both formulations of semaglutide (oral and subcutaneous) can provide clinical improvements in the key management goals (glycaemic control and weight loss) for individuals living with T2D [30]
Patients should aim for consistent daily fiber intake rather than sporadic high-fiber days, as regularity supports predictable bowel function
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