She says this is usually done through broader genetic panels ordered by a doctor, rather than testing for the gene on its own
One of the most common and devastating severe manifestations of SLE is lupus nephritis (LN), which affects an estimated 40-70% of lupus patients
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Blinded allocation, centralized measurement of renal endpoints, and high retention rates support confidence in directionality of effect, while limitations arise primarily from study duration, sample size, and surrogate endpoints (albuminuria, eGFR slope)
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