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Care models will continue to become more integrated

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Potential Benefits in Research Weight Management Research Significant body weight reduction (up to 24% in trials) Enhanced appetite suppression through central mechanisms Improved satiety signaling Sustainable weight loss maintenance Metabolic Health Improved insulin sensitivity and glucose metabolism Enhanced lipid profile (cholesterol and triglycerides) Reduced hepatic fat accumulation Improved glycemic control in diabetic models Cardiovascular Research Blood pressure reduction in research subjects Improved cardiovascular risk markers Reduced inflammation markers (CRP, IL-6) Enhanced endothelial function Safety Profile Important: These side effects are reported from research studies and may vary by individual, dosage, and protocol

Endocrine 66 (2), 157165 (2019)

Effects of a proposed physical activity and diet control to manage constipation in middle-aged obese women