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doi: 10.3389/fmed.2026.1763185 Received 08 December 2025 Revised 20 January 2026 Accepted 26 January 2026 Published 12 February 2026 Volume 13 - 2026 Edited by Jianbin Zhang, Dalian Medical University, China Reviewed by Theodoros Androutsakos, National and Kapodistrian University of Athens, Greece Feng Zhang, Nanjing University of Chinese Medicine, China Updates Copyright 2026 Lu and Yang

Prolactin elevation can cause sexual dysfunction and other endocrine effects

Moreover, tirzepatide outperformed semaglutide when it came to weight loss, with tirzepatide doses of 15 mg, 10 mg, and 5 mg delivering notable reductions in body weight (-10.96 Kg, -8.75 Kg, and -6.16 Kg, respectively) compared to semaglutide (-5.24 Kg, -4.44 Kg, and -2.72 Kg for semaglutide at 2.0, 1.0, and 0.5 mg, respectively)

And in order to ensure continuous development, even if we are seeing good efficacy, it is important to keep building our understanding of how these drugs are working by looking into things like mode of action and pathophysiology

Declining oestrogen from menopause plus declining oestrogen from fat loss plus reduced nutrient intake thats three simultaneous mechanisms working against your hair

It performs best for a specific patient profile, and being honest about that profile is part of how we get good results at Perfect B