The updated shots have a single target, an omicron descendant named XBB.1.5
Pre-filling syringes exposes the medication to additional contamination risk and removes it from the preservative environment of the vial
PSCI affects a significant proportion of survivors, manifesting as deficits in memory, executive function, and attention that markedly diminish quality of life and functional independence
Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant
It has a half-life of approximately six days, which supports once-weekly subcutaneous injection
Theres also supporting animal data