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Nutrition support and a non-restrictive, balanced approach to eating are essential components of any responsible use of these medications

This initial response happens because semaglutide activates GLP-1 receptors in your brain's appetite control centers, signaling fullness and slowing stomach emptying

Constipation hits approximately 24% of Wegovy users and 20-25% of Zepbound users

Clinical implications: When used together, Wegovy's glucose-lowering effects may help partially mitigate prednisolone's tendency to raise blood sugar levels

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But for many, semaglutide has changed the story