A perspective
Massage onto cleansed face and neck in the evening using a gentle upward motion
10.1016/j.mam.2008.05.005 Mol Aspects Med
You specifically want FDA-approved medications rather than compounded formulations, since the brand states plainly that compounded medications are not FDA-approved and are not reviewed by FDA before marketing
Dosing and Administration Topical use: Apply as directed by the product (usually once or twice daily)
Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cell therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills, and other US cities