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Also, the fourth melanocortin receptor, MC-4R, is involved in the regulation of sexual activity, which is why Melanotan 2 has been found to have a significant effect on increasing libido and improving erectile function

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Adv Healthc Mater 14:2403840 Zhang X, Wang Y, Liu J, Shi J, Mao D, Midgley AC et al (2021) A metal-organic-framework incorporated vascular graft for sustained nitric oxide generation and long-term vascular patency