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The imidizaole ring on the carnosine, is able to mop up the hydrogen ions

Patients with advanced prostate cancer are often treated with endocrine therapy including maximal androgen blockade (anti-androgens combined with castration) and classical androgen deprivation (orchiectomy or luteinizing hormone-releasing hormone agonists) [5]

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mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

We note that without information on peoples BMI and underlying medical risk factors, it is not possible to determine whether this reflects a genuine medical need