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Of them, sodium ferulate (SF) features low toxicity, stability, ease of synthesis, and water solubility and has been authorized by the State Drug Administration of China as an adjuvant drug for treating ischemic cardiovascular diseases [166, 167]
73 Besides, the PKA pathway may also be involved in GLP-1, attenuating the ER stress signaling pathway and protecting cells from apoptosis
While this mechanism remains speculative, the underlying physiology of cryotherapy-induced blood flow changes supports the concept