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Lpez-Otn et al., Cell, 2023 Backed by Landmark Clinical Trials The efficacy and safety of semaglutide are supported by extensive research, including the large-scale STEP and SELECT clinical trial programs

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Weight reduction can sometimes lead to small decreases in TSH levels and may reduce levothyroxine requirements in some patients with hypothyroidism

And also with food or without which is a good segue to another question but yes when to take it

5.3 Clinical evidence regarding GLP-1 and taste In the past few years, there has been growing evidence that highlights the physiological and molecular mechanisms in which GLP-1 regulates taste perception