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Cytoplasmic and Mitochondrial Tetrahydrofolate Interconversions A member of the folate metabolism family of enzymes, encoded by the MTHFD1 gene, can generate NADPH in the course of the conversion of N 5 , N 10 -methylene-tetrahydrofolate (5,10-methylene-THF) to 5,10-methenyl-THF

doi: 10.3389/fmed.2022.828240 185 HaoJWangSGuoXGuoXHaoL

GLP-1 agonists affect diverse obesity etiopathogenic processes such as abnormal food intake regulation, adipocyte dysfunction, insulin resistance, adipokine production, inflammation, endothelial dysfunction, lipid metabolism, and oxidative stress

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Smith JR, Thiagaraj HV, Seaver B, Parker KK