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If it has a role, its more like a supporting actor than a lead therapy
Finally, another layer of complexity is added when considering the evidence of a leaky bloodbrain barrier across several neuropsychiatric disorders 255 , which could further increase the brain penetrance of GLP-1RAs administered to people with such illnesses
F., & STEP 1 Study Group (2021)
What Are the Wellness Benefits of Glutathione IV Therapy
If tirzepatide causes you to become dehydrated, and you are already on bupropion which has lowered your seizure threshold, the combined situation could increase seizure risk beyond what either medication would cause independently
