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Its conceptual foundation came from the observation that gastric mucosa survives in an environment exposed to acid, enzymes, and mechanical stress
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Although the literature is split with respect to OPC number in the aged brain, their ability to differentiate is severely impaired in humans and rodents (Sim et al., 2002
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Preclinical studies have demonstrated that extended GLP-1 RA exposure can lead to ductal hyperplasia, increased pancreatic mass, and tissue remodeling [7,8,9,10]
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